Reliability of striatal [11C]raclopride binding in smokers wearing transdermal nicotine patches

Side effects of transdermal nicotine patches.

Targeting heavy smokers in general practice: randomised controlled trial of transdermal nicotine patches.

OBJECTIVES (a) To evaluate the efficacy of transdermal nicotine patches as an aid to stopping smoking when used as an adjunct to brief advice and support in a general practice setting; (b) to see whether an increase in nicotine patch dosage enhances the rate of initial cessation. DESIGN Randomised double blind placebo controlled parallel group study with one year of follow up. SETTING 30 ge...

Childhood poisoning involving transdermal nicotine patches.

OBJECTIVE To describe the circumstances, medical complications, and outcomes of children exposed to a transdermal nicotine patch (TNP). DESIGN Prospective case series; postmarketing surveillance study over a 24-month period. SETTING Thirty-four United States poison centers. Patients. Children 0 to 15 years old exposed to a TNP. INTERVENTIONS None. OUTCOME MEASURES Exposure circumstances...

Effects of high dose transdermal nicotine replacement in cigarette smokers.

RATIONALE Nicotine replacement therapies (NRT) have been evaluated to facilitate cigarette smoking reduction in smokers unwilling or unable to quit. In most of these studies, only conventional doses of NRT have been tested and higher doses may be required to result in significant reductions in smoking and in biomarkers of exposure. OBJECTIVE To determine if higher NRT doses in conjunction wit...

The effect of transdermal nicotine patches on sleep and dreams.

This study was undertaken to determine the effect of 24-h transdermal nicotine patches on sleep and dream mentation in 15 smokers aged 20 to 33. Utilising a repeated measures design, it was found that more time awake and more ASDA micro-arousals occurred while wearing the nicotine patch compared to placebo. Also, the percentage of REM sleep decreased, but REM latency and the proportion of time ...